Los Angeles Chargers vs Buffalo Bills

atChargers at Bills

Week 3

September 27 · 1:00 PM EDT

· BUF -3 · O/U 48.5

The read

Momentum cuts both ways: LAC arrive coming off a loss, BUF on a 2-game win streak.

What's at stake

Where a win or a loss leaves each side.

Where they standLast 5Last 5Record

Los Angeles Chargers1st in the AFC WestLWLLLL10-0Away

Buffalo Bills1st in the AFC EastWWLWWW20-0Home

Injury report

Who is unavailable, in each club’s own words to the league. A day-to-day designation still allows a start, so a name here is not always a scratch; an injured-list stint is.

Los Angeles Chargers5 listed

Keaton MitchellRB · is questionable. Back 2026-08-27.

Brenen ThompsonWR · is questionable. Back 2026-08-27.

Tyler BiadaszCatcher · is listed injured reserve. Back 2027-02-15.

Tre' HarrisWR · is questionable. Back 2026-08-27.

Rashawn SlaterOT · is questionable. Back 2026-08-27.

Buffalo Bills5 listed

Khalil ShakirWR · is questionable. Back 2026-09-13.

Keon ColemanWR · is questionable. Back 2026-09-13.

Ty JohnsonRB · is questionable. Back 2026-09-13.

Terrel BernardLB · is questionable. Back 2026-09-13.

Jude BowryOT · is questionable. Back 2026-08-27.

Projected starting lineups

Each club's published depth chart, top of the order at every spot. A chart is not a game plan, and coaches confirm the actual card closer to kickoff.

Los Angeles ChargersDepth chart

Offense11

Justin Herbert#106' 6"7 yr

Omarion Hampton#86' 0"2 yr

Ladd McConkey#156' 0"3 yr

Quentin Johnston#16' 2"4 yrQuestionable

Tre' Harris#96' 3"2 yrQuestionable

Charlie Kolar#886' 6"5 yr

Rashawn Slater#706' 4"6 yrQuestionable

Kayode Awosika#746' 3"5 yr

Jake Slaughter#666' 5"Rookie

Cole Strange#696' 5"5 yr

Joe Alt#766' 8"3 yr

Defense11

LDE

Teair Tart#936' 2"7 yr

Dalvin Tomlinson#946' 3"10 yr

RDE

Jamaree Caldwell#996' 1"2 yr

WLB

Tuli Tuipulotu#456' 3"4 yr

LILB

Daiyan Henley#06' 0"4 yr

RILB

Denzel Perryman#65' 11"12 yr

SLB

Khalil Mack#526' 3"13 yr

LCB

Cam Hart#206' 2"3 yr

RCB

Donte Jackson#265' 10"8 yr

Derwin James Jr.#36' 2"9 yr

Elijah Molden#25' 10"6 yr

Special teams5

Cameron Dicker#116' 1"5 yr

JK Scott#166' 5"8 yr

Josh Harris#476' 1"15 yr

Derius Davis#125' 8"4 yr

Buffalo BillsDepth chart

Offense11

Josh Allen#176' 5"9 yr

James Cook III#45' 11"5 yr

DJ Moore#26' 0"9 yr

Khalil Shakir#106' 0"5 yrQuestionable

Keon Coleman#06' 3"3 yrQuestionable

Dalton Kincaid#866' 3"4 yr

Dion Dawkins#736' 5"10 yr

Alec Anderson#706' 5"4 yr

Connor McGovern#666' 6"8 yrQuestionable

O'Cyrus Torrence#646' 5"4 yr

Spencer Brown#796' 8"6 yr

Defense11

LDE

T.J. Sanders#986' 4"2 yr

Deone Walker#966' 7"2 yr

RDE

Ed Oliver#916' 1"8 yr

WLB

Greg Rousseau#156' 6"6 yr

LILB

Dorian Williams#426' 1"4 yr

RILB

Terrel Bernard#86' 1"5 yrQuestionable

SLB

Bradley Chubb#96' 4"9 yr

LCB

Christian Benford#476' 1"5 yr

RCB

Maxwell Hairston#315' 11"2 yr

Cole Bishop#246' 2"2 yr

Geno Stone#255' 11"7 yr

Special teams5

Tyler Bass#165' 10"7 yr

Mitch Wishnowsky#196' 2"8 yr

Reid Ferguson#696' 2"10 yr

Ray Davis#75' 8"3 yr

Khalil Shakir#106' 0"5 yrQuestionable

League standings

The full ladder, with both clubs marked.

AFC East

#ClubW-LPCTStreak

1Buffalo Bills2-01.000W2

2New England Patriots1-0.750W1

3New York Jets1-1.500W1

4Miami Dolphins0-2.000L2

AFC North

#ClubW-LPCTStreak

1Cincinnati Bengals2-01.000W2

2Baltimore Ravens2-01.000W2

3Pittsburgh Steelers1-1.500L1

4Cleveland Browns0-2.000L2

AFC South

#ClubW-LPCTStreak

1Tennessee Titans2-01.000W2

2Jacksonville Jaguars1-1.500L1

3Indianapolis Colts0-1.250L1

4Houston Texans0-2.000L2

AFC West

#ClubW-LPCTStreak

1Los Angeles Chargers1-1.500L1

2Las Vegas Raiders1-1.500W1

3Denver Broncos1-1.500L1

4Kansas City Chiefs0-2.000L2

NFC East

#ClubW-LPCTStreak

1Dallas Cowboys2-01.000W2

2Washington Commanders1-1.500L1

3New York Giants1-1.500W1

4Philadelphia Eagles0-2.000L2

NFC North

#ClubW-LPCTStreak

1Detroit Lions1-1.500W1

2Minnesota Vikings1-1.500L1

3Green Bay Packers1-1.500W1

4Chicago Bears1-1.500L1

NFC South

#ClubW-LPCTStreak

1Tampa Bay Buccaneers2-01.000W2

2Carolina Panthers2-1.667W1

3Atlanta Falcons1-1.500W1

4New Orleans Saints0-2.000L2

NFC West

#ClubW-LPCTStreak

1Los Angeles Rams2-01.000W2

2San Francisco 49ers1-1.500W1

3Arizona Cardinals1-2.333L1

4Seattle Seahawks0-2.000L2

Win probability

Los Angeles Chargers

40%

Buffalo Bills

60%

Chargers at Bills

Los Angeles

Chargers

Buffalo

Bills

Post Game SummaryStat Savant

atChargers at Bills

Week 3

September 27 · 1:00 PM EDT

· BUF -3 · O/U 48.5

The read

Momentum cuts both ways: LAC arrive coming off a loss, BUF on a 2-game win streak.

What's at stake

Where a win or a loss leaves each side.

Where they standLast 5Last 5Record

Los Angeles Chargers1st in the AFC WestLWLLLL10-0Away

Buffalo Bills1st in the AFC EastWWLWWW20-0Home

Injury report

Who is unavailable, in each club’s own words to the league. A day-to-day designation still allows a start, so a name here is not always a scratch; an injured-list stint is.

Los Angeles Chargers5 listed

Keaton MitchellRB · is questionable. Back 2026-08-27.

Brenen ThompsonWR · is questionable. Back 2026-08-27.

Tyler BiadaszCatcher · is listed injured reserve. Back 2027-02-15.

Tre' HarrisWR · is questionable. Back 2026-08-27.

Rashawn SlaterOT · is questionable. Back 2026-08-27.

Buffalo Bills5 listed

Khalil ShakirWR · is questionable. Back 2026-09-13.

Keon ColemanWR · is questionable. Back 2026-09-13.

Ty JohnsonRB · is questionable. Back 2026-09-13.

Terrel BernardLB · is questionable. Back 2026-09-13.

Jude BowryOT · is questionable. Back 2026-08-27.

Projected starting lineups

Each club's published depth chart, top of the order at every spot. A chart is not a game plan, and coaches confirm the actual card closer to kickoff.

Los Angeles ChargersDepth chart

Offense11

Justin Herbert#106' 6"7 yr

Omarion Hampton#86' 0"2 yr

Ladd McConkey#156' 0"3 yr

Quentin Johnston#16' 2"4 yrQuestionable

Tre' Harris#96' 3"2 yrQuestionable

Charlie Kolar#886' 6"5 yr

Rashawn Slater#706' 4"6 yrQuestionable

Kayode Awosika#746' 3"5 yr

Jake Slaughter#666' 5"Rookie

Cole Strange#696' 5"5 yr

Joe Alt#766' 8"3 yr

Defense11

LDE

Teair Tart#936' 2"7 yr

Dalvin Tomlinson#946' 3"10 yr

RDE

Jamaree Caldwell#996' 1"2 yr

WLB

Tuli Tuipulotu#456' 3"4 yr

LILB

Daiyan Henley#06' 0"4 yr

RILB

Denzel Perryman#65' 11"12 yr

SLB

Khalil Mack#526' 3"13 yr

LCB

Cam Hart#206' 2"3 yr

RCB

Donte Jackson#265' 10"8 yr

Derwin James Jr.#36' 2"9 yr

Elijah Molden#25' 10"6 yr

Special teams5

Cameron Dicker#116' 1"5 yr

JK Scott#166' 5"8 yr

Josh Harris#476' 1"15 yr

Derius Davis#125' 8"4 yr

Buffalo BillsDepth chart

Offense11

Josh Allen#176' 5"9 yr

James Cook III#45' 11"5 yr

DJ Moore#26' 0"9 yr

Khalil Shakir#106' 0"5 yrQuestionable

Keon Coleman#06' 3"3 yrQuestionable

Dalton Kincaid#866' 3"4 yr

Dion Dawkins#736' 5"10 yr

Alec Anderson#706' 5"4 yr

Connor McGovern#666' 6"8 yrQuestionable

O'Cyrus Torrence#646' 5"4 yr

Spencer Brown#796' 8"6 yr

Defense11

LDE

T.J. Sanders#986' 4"2 yr

Deone Walker#966' 7"2 yr

RDE

Ed Oliver#916' 1"8 yr

WLB

Greg Rousseau#156' 6"6 yr

LILB

Dorian Williams#426' 1"4 yr

RILB

Terrel Bernard#86' 1"5 yrQuestionable

SLB

Bradley Chubb#96' 4"9 yr

LCB

Christian Benford#476' 1"5 yr

RCB

Maxwell Hairston#315' 11"2 yr

Cole Bishop#246' 2"2 yr

Geno Stone#255' 11"7 yr

Special teams5

Tyler Bass#165' 10"7 yr

Mitch Wishnowsky#196' 2"8 yr

Reid Ferguson#696' 2"10 yr

Ray Davis#75' 8"3 yr

Khalil Shakir#106' 0"5 yrQuestionable

League standings

The full ladder, with both clubs marked.

AFC East

#ClubW-LPCTStreak

1Buffalo Bills2-01.000W2

2New England Patriots1-0.750W1

3New York Jets1-1.500W1

4Miami Dolphins0-2.000L2

AFC North

#ClubW-LPCTStreak

1Cincinnati Bengals2-01.000W2

2Baltimore Ravens2-01.000W2

3Pittsburgh Steelers1-1.500L1

4Cleveland Browns0-2.000L2

AFC South

#ClubW-LPCTStreak

1Tennessee Titans2-01.000W2

2Jacksonville Jaguars1-1.500L1

3Indianapolis Colts0-1.250L1

4Houston Texans0-2.000L2

AFC West

#ClubW-LPCTStreak

1Los Angeles Chargers1-1.500L1

2Las Vegas Raiders1-1.500W1

3Denver Broncos1-1.500L1

4Kansas City Chiefs0-2.000L2

NFC East

#ClubW-LPCTStreak

1Dallas Cowboys2-01.000W2

2Washington Commanders1-1.500L1

3New York Giants1-1.500W1

4Philadelphia Eagles0-2.000L2

NFC North

#ClubW-LPCTStreak

1Detroit Lions1-1.500W1

2Minnesota Vikings1-1.500L1

3Green Bay Packers1-1.500W1

4Chicago Bears1-1.500L1

NFC South

#ClubW-LPCTStreak

1Tampa Bay Buccaneers2-01.000W2

2Carolina Panthers2-1.667W1

3Atlanta Falcons1-1.500W1

4New Orleans Saints0-2.000L2

NFC West

#ClubW-LPCTStreak

1Los Angeles Rams2-01.000W2

2San Francisco 49ers1-1.500W1

3Arizona Cardinals1-2.333L1

4Seattle Seahawks0-2.000L2

Win probability

Los Angeles Chargers

40%

Buffalo Bills

60%

Los Angeles Chargers vs Buffalo Bills — Sep 27, 2026

The read

What's at stake

Injury report

Projected starting lineups

League standings

Win probability

Los Angeles Chargers vs Buffalo Bills — Sep 27, 2026

The read

What's at stake

Injury report

Projected starting lineups

League standings

Win probability