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Stat SavantPremium issuesMy teams

Buffalo Bills vs Los Angeles Rams Preview & How to Watch, Oct 12, 2026

NFL · 8:15 PM EDT · Mon, Oct 12, 2026 · ESPN
SoFi StadiumSoFi Stadium · Inglewood, CA
Preview
Moneyline
Win prob.
Buffalo Bills3-1-0 · 1-0 away
+146
48%
Los Angeles Rams2-2-0 · 1-1 home
−176
52%
Total 54.5
Box score and highlights appear here at kickoff.

Monday, 8:15 PM ET on ESPN. Rams by 3.5.

The Rams host the Bills on Monday, Oct 12, at SoFi Stadium. Kickoff is 8:15 PM ET (7:15 CT, 6:15 MT, 5:15 PT) on ESPN, ABC. Los Angeles is a 3.5-point favorite, and the line gives them a 61% chance to win.

How we get these numbers

How to watch

Matchup
Bills atRams
Kickoff
Mon, Oct 12 · 8:15 PM ET · 7:15 CT · 6:15 MT · 5:15 PT
TV
ESPN, ABC
Where
SoFi Stadium, Inglewood, CA
Add the Rams to your calendar

Bills at Rams

Los Angeles is down four to injury.

What decides it

Our model projects Bills 27, Rams 28, leaning Rams.

The number starts from the market line and is adjusted for recent form and availability.

The two clubs · this season
BUF
LAR
Edge
Total Yards
398.8
427.3
LAR
Recent form
Last 5, oldest first
Buffalo
L W W W W
Los Angeles
W L W L W
Season to date. The full comparison is on Stat Savant.
Quarterbacks
Comp/Att
Yards
TD
INT
J. Allen
Buffalo
79/119
1039
6
3
M. Stafford
Los Angeles
99/162
1189
6
6
Out tonight
Los Angeles Rams
Pos
Myles Garrett
DE
Terrance Ferguson
TE
Ronnie Rivers
RB
Keir Thomas II
LB
Buffalo Bills
Pos
Ed Oliver
DT
Joshua Palmer
WR

Questions

What channel is the Bills vs Rams game on?

ESPN, ABC, Monday at 8:15 PM ET.

What time is the Bills vs Rams game?

8:15 PM ET on Monday, Oct 12, which is 5:15 PT.

Who is favored, the Bills or the Rams?

The Rams, by 3.5 points. The line gives them a 61% chance to win.

Our number
LAR 28
BUF 27
Projected points. The model makes Rams a 52% favorite. Medium confidence.
The line
Now
Moneyline
LAR −176 · BUF +146
Spread
LAR -3.5
Total
54.5
Moneyline opened LAR −148, now −176. Spread opened LAR −2.5, now −3.5. Total opened 53.5, now 54.5.
NFC West
W
L
PCT
49ers
5
0
1.000
Seahawks
3
2
.600
Rams
2
2
.500
Cardinals
1
4
.200
Bills vs. Rams: every meeting since 2016 →

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Game emails · free

Your teams, before and after every game.

A preview two hours before the start and the box score minutes after the final. Free, and every email has its own off switch.

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Today’s games
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Playoff pictureNFL playoff scheduleCFP pictureCFB rankingsCFB standingsHeisman watchBowl gamesConference title gamesCBB rankingsCBB tonightCBB preview 2026-27CBB transfer portalNFL scheduleMonday Night FootballNFL trade trackerNFL stat leadersCFB scheduleNFL draft orderSchedule strengthNFL rivalriesNFL injury reportNFL defense rankingsNBA injury reportNBA matchupsNHL matchupsCFB matchups
Most followed
Dallas CowboysKansas City ChiefsNew York YankeesBuffalo BillsDetroit LionsChicago BearsPittsburgh SteelersGreen Bay PackersNew York GiantsChicago CubsBoston Red SoxNotre Dame
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Fantasy tools+−
Start/sit rankingsLineup checkWho’s playing tonightTrade analyzerTrade value chartWaiver wireYour Sleeper leagueDefense vs positionFantasy playoff scheduleNFL bye weeksNHL schedule gridNBA schedule gridHockey streamers
Betting tools & picks+−
Odds converterParlay calculatorHedge calculatorExpected valueBet size (Kelly)Teasers, round robinsLine movementClosing line valuePrediction marketsNFL picksCollege football picks
Standings & playoffs+−
Playoff pictureNFL playoff scheduleCFP pictureCFB rankingsCFB standingsHeisman watchBowl gamesConference title gamesCBB rankingsCBB tonightCBB preview 2026-27
Leagues+−
NFLCollege footballMLBNBANHLWNBACollege basketballToday’s games
Most followed+−
Dallas CowboysKansas City ChiefsNew York YankeesBuffalo BillsDetroit LionsChicago BearsPittsburgh SteelersGreen Bay PackersNew York GiantsChicago CubsBoston Red Sox
Read+−
Top plays last nightPlayer highlightsMLB walk-offsNews WireStat SavantBest BetsNFL preview 2026College football 2026Premium issuesBox Scores newsletterHow it worksHow we get our numbers
Highlights+−
Major League planInvite friendsPrivacyTermsLog in
A Mainmarket brand · 135 York St, Brooklyn, NY 11201 · Not affiliated with any league or team
Betting tools are for information. 21+. Gambling problem? Call 1-800-GAMBLER.

Scores, schedules, rosters and statistics come from public sports data feeds and are for information only. Odds, projections and win probabilities are for entertainment only and are not betting advice. Team names and marks belong to their owners and identify the clubs we cover. © 2026 MainMarket.com. All rights reserved.

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Notre Dame

Best odds for Bills vs Rams

Every line on Best Bets
Bills +150 at BetMGM
$5 more on a winning $100 than Fanatics (+145)
Rams −175 at DraftKings
$3.09 more on a winning $100 than BetMGM (−185)

Moneyline, from the books we track at the last odds sync. Prices, not picks. 21+, where legal.