San Francisco 49ers vs Kansas City Chiefs

at49ers at Chiefs

Week 16

December 27 · 4:25 PM EST

· KC -3 · O/U 46.5

The read

There's a playoff line running through this one: 49ers sit in a postseason spot, while Chiefs are on the outside chasing a crossover, so it means a little more to the club playing from behind. Momentum cuts both ways: SF arrive on a 1-game win streak, KC coming off a loss.

What's at stake

Where a win or a loss leaves each side.

Where they standLast 5Last 5Record

San Francisco 49ers2nd in the NFC West, 1 backWLLWLW10-0Away

Kansas City Chiefs4th in the AFC West, 1 backLLLLLL20-0Home

Injury report

Who is unavailable, in each club’s own words to the league. A day-to-day designation still allows a start, so a name here is not always a scratch; an injured-list stint is.

San Francisco 49ers5 listed

De'Zhaun StriblingWR · is questionable. Back 2026-08-27.

Victor DimukejeDE · is listed injured reserve. Back 2027-02-15.

Mike EvansWR · is questionable. Back 2026-09-10.

Robert JonesG · is questionable. Back 2026-09-10.

Kurtis RourkeQB · is questionable. Back 2026-09-10.

Kansas City Chiefs5 listed

Kenneth Walker IIIRB · is questionable. Back 2026-08-28.

Jeff CaldwellWR · is listed injured reserve. Back 2027-02-15.

Tyreke SmithDE · is questionable. Back 2026-08-28.

Patrick MahomesQB · is questionable. Back 2026-08-28.

Alohi GilmanS · is questionable. Back 2026-08-28.

Projected starting lineups

Each club's published depth chart, top of the order at every spot. A chart is not a game plan, and coaches confirm the actual card closer to kickoff.

San Francisco 49ersDepth chart

Offense11

Brock Purdy#136' 1"5 yr

Christian McCaffrey#235' 11"10 yrQuestionable

Mike Evans#56' 5"13 yrQuestionable

Deebo Samuel Sr.#196' 0"8 yr

De'Zhaun Stribling#156' 2"RookieQuestionable

George Kittle#856' 4"10 yrQuestionable

Trent Williams#716' 5"17 yr

Robert Jones#656' 4"6 yrQuestionable

Jake Brendel#646' 4"9 yr

Dominick Puni#776' 5"3 yrQuestionable

Colton McKivitz#686' 6"7 yr

Defense11

LDE

C.J. West#996' 1"2 yr

Alfred Collins#956' 5"2 yr

RDE

Osa Odighizuwa#926' 2"6 yr

WLB

Nick Bosa#976' 4"8 yrQuestionable

LILB

Dre Greenlaw#576' 0"8 yr

RILB

Fred Warner#546' 3"9 yr

SLB

Mykel Williams#986' 5"2 yrOut

LCB

Deommodore Lenoir#25' 10"6 yr

RCB

Renardo Green#06' 0"3 yrQuestionable

Ji'Ayir Brown#275' 11"4 yr

Malik Mustapha#65' 10"3 yrQuestionable

Special teams5

Eddy Pineiro#185' 11"9 yr

Corliss Waitman#76' 2"4 yr

Jon Weeks#465' 10"17 yr

Isaac Guerendo#316' 0"3 yrOut

Jacob Cowing#65' 9"3 yrQuestionable

Kansas City ChiefsDepth chart

Offense11

Patrick Mahomes#156' 2"10 yrQuestionable

Kenneth Walker III#95' 9"5 yrQuestionable

Rashee Rice#46' 1"4 yr

Xavier Worthy#15' 11"3 yrQuestionable

Tyquan Thornton#26' 2"5 yr

Travis Kelce#876' 5"14 yr

Josh Simmons#716' 5"2 yr

Kingsley Suamataia#766' 4"3 yr

Creed Humphrey#526' 4"6 yr

Trey Smith#656' 6"6 yrQuestionable

Kahlil Benson#706' 6"Rookie

Defense11

LDE

George Karlaftis#566' 4"5 yr

LDT

Chris Jones#956' 6"11 yr

RDT

Khyiris Tonga#926' 2"6 yr

RDE

Felix Anudike-Uzomah#916' 4"4 yr

WLB

Drue Tranquill#236' 2"8 yrQuestionable

MLB

Nick Bolton#325' 11"6 yr

SLB

Cole Christiansen#486' 1"2 yr

LCB

L'Jarius Sneed#386' 1"7 yrQuestionable

RCB

Mansoor Delane#56' 0"Rookie

Chamarri Conner#276' 0"4 yr

Alohi Gilman#175' 10"7 yrQuestionable

Special teams5

Harrison Butker#76' 4"10 yr

Matt Araiza#146' 1"3 yr

James Winchester#416' 3"12 yr

Nikko Remigio#815' 9"2 yr

League standings

The full ladder, with both clubs marked.

AFC East

#ClubW-LPCTStreak

1Buffalo Bills2-01.000W2

2New England Patriots1-0.750W1

3New York Jets1-1.500W1

4Miami Dolphins0-2.000L2

AFC North

#ClubW-LPCTStreak

1Cincinnati Bengals2-01.000W2

2Baltimore Ravens2-01.000W2

3Pittsburgh Steelers1-1.500L1

4Cleveland Browns0-2.000L2

AFC South

#ClubW-LPCTStreak

1Tennessee Titans2-01.000W2

2Jacksonville Jaguars1-1.500L1

3Indianapolis Colts0-1.250L1

4Houston Texans0-2.000L2

AFC West

#ClubW-LPCTStreak

1Los Angeles Chargers1-1.500L1

2Las Vegas Raiders1-1.500W1

3Denver Broncos1-1.500L1

4Kansas City Chiefs0-2.000L2

NFC East

#ClubW-LPCTStreak

1Dallas Cowboys2-01.000W2

2Washington Commanders1-1.500L1

3New York Giants1-1.500W1

4Philadelphia Eagles0-2.000L2

NFC North

#ClubW-LPCTStreak

1Detroit Lions1-1.500W1

2Minnesota Vikings1-1.500L1

3Green Bay Packers1-1.500W1

4Chicago Bears1-1.500L1

NFC South

#ClubW-LPCTStreak

1Tampa Bay Buccaneers2-01.000W2

2Carolina Panthers2-1.667W1

3Atlanta Falcons1-1.500W1

4New Orleans Saints0-2.000L2

NFC West

#ClubW-LPCTStreak

1Los Angeles Rams2-01.000W2

2San Francisco 49ers1-1.500W1

3Arizona Cardinals1-2.333L1

4Seattle Seahawks0-2.000L2

Win probability

San Francisco 49ers

49%

Kansas City Chiefs

51%

49ers at Chiefs

San Francisco

49ers

Kansas City

Chiefs

Post Game SummaryStat Savant

at49ers at Chiefs

Week 16

December 27 · 4:25 PM EST

· KC -3 · O/U 46.5

The read

What's at stake

Where a win or a loss leaves each side.

Where they standLast 5Last 5Record

San Francisco 49ers2nd in the NFC West, 1 backWLLWLW10-0Away

Kansas City Chiefs4th in the AFC West, 1 backLLLLLL20-0Home

Injury report

Who is unavailable, in each club’s own words to the league. A day-to-day designation still allows a start, so a name here is not always a scratch; an injured-list stint is.

San Francisco 49ers5 listed

De'Zhaun StriblingWR · is questionable. Back 2026-08-27.

Victor DimukejeDE · is listed injured reserve. Back 2027-02-15.

Mike EvansWR · is questionable. Back 2026-09-10.

Robert JonesG · is questionable. Back 2026-09-10.

Kurtis RourkeQB · is questionable. Back 2026-09-10.

Kansas City Chiefs5 listed

Kenneth Walker IIIRB · is questionable. Back 2026-08-28.

Jeff CaldwellWR · is listed injured reserve. Back 2027-02-15.

Tyreke SmithDE · is questionable. Back 2026-08-28.

Patrick MahomesQB · is questionable. Back 2026-08-28.

Alohi GilmanS · is questionable. Back 2026-08-28.

Projected starting lineups

Each club's published depth chart, top of the order at every spot. A chart is not a game plan, and coaches confirm the actual card closer to kickoff.

San Francisco 49ersDepth chart

Offense11

Brock Purdy#136' 1"5 yr

Christian McCaffrey#235' 11"10 yrQuestionable

Mike Evans#56' 5"13 yrQuestionable

Deebo Samuel Sr.#196' 0"8 yr

De'Zhaun Stribling#156' 2"RookieQuestionable

George Kittle#856' 4"10 yrQuestionable

Trent Williams#716' 5"17 yr

Robert Jones#656' 4"6 yrQuestionable

Jake Brendel#646' 4"9 yr

Dominick Puni#776' 5"3 yrQuestionable

Colton McKivitz#686' 6"7 yr

Defense11

LDE

C.J. West#996' 1"2 yr

Alfred Collins#956' 5"2 yr

RDE

Osa Odighizuwa#926' 2"6 yr

WLB

Nick Bosa#976' 4"8 yrQuestionable

LILB

Dre Greenlaw#576' 0"8 yr

RILB

Fred Warner#546' 3"9 yr

SLB

Mykel Williams#986' 5"2 yrOut

LCB

Deommodore Lenoir#25' 10"6 yr

RCB

Renardo Green#06' 0"3 yrQuestionable

Ji'Ayir Brown#275' 11"4 yr

Malik Mustapha#65' 10"3 yrQuestionable

Special teams5

Eddy Pineiro#185' 11"9 yr

Corliss Waitman#76' 2"4 yr

Jon Weeks#465' 10"17 yr

Isaac Guerendo#316' 0"3 yrOut

Jacob Cowing#65' 9"3 yrQuestionable

Kansas City ChiefsDepth chart

Offense11

Patrick Mahomes#156' 2"10 yrQuestionable

Kenneth Walker III#95' 9"5 yrQuestionable

Rashee Rice#46' 1"4 yr

Xavier Worthy#15' 11"3 yrQuestionable

Tyquan Thornton#26' 2"5 yr

Travis Kelce#876' 5"14 yr

Josh Simmons#716' 5"2 yr

Kingsley Suamataia#766' 4"3 yr

Creed Humphrey#526' 4"6 yr

Trey Smith#656' 6"6 yrQuestionable

Kahlil Benson#706' 6"Rookie

Defense11

LDE

George Karlaftis#566' 4"5 yr

LDT

Chris Jones#956' 6"11 yr

RDT

Khyiris Tonga#926' 2"6 yr

RDE

Felix Anudike-Uzomah#916' 4"4 yr

WLB

Drue Tranquill#236' 2"8 yrQuestionable

MLB

Nick Bolton#325' 11"6 yr

SLB

Cole Christiansen#486' 1"2 yr

LCB

L'Jarius Sneed#386' 1"7 yrQuestionable

RCB

Mansoor Delane#56' 0"Rookie

Chamarri Conner#276' 0"4 yr

Alohi Gilman#175' 10"7 yrQuestionable

Special teams5

Harrison Butker#76' 4"10 yr

Matt Araiza#146' 1"3 yr

James Winchester#416' 3"12 yr

Nikko Remigio#815' 9"2 yr

League standings

The full ladder, with both clubs marked.

AFC East

#ClubW-LPCTStreak

1Buffalo Bills2-01.000W2

2New England Patriots1-0.750W1

3New York Jets1-1.500W1

4Miami Dolphins0-2.000L2

AFC North

#ClubW-LPCTStreak

1Cincinnati Bengals2-01.000W2

2Baltimore Ravens2-01.000W2

3Pittsburgh Steelers1-1.500L1

4Cleveland Browns0-2.000L2

AFC South

#ClubW-LPCTStreak

1Tennessee Titans2-01.000W2

2Jacksonville Jaguars1-1.500L1

3Indianapolis Colts0-1.250L1

4Houston Texans0-2.000L2

AFC West

#ClubW-LPCTStreak

1Los Angeles Chargers1-1.500L1

2Las Vegas Raiders1-1.500W1

3Denver Broncos1-1.500L1

4Kansas City Chiefs0-2.000L2

NFC East

#ClubW-LPCTStreak

1Dallas Cowboys2-01.000W2

2Washington Commanders1-1.500L1

3New York Giants1-1.500W1

4Philadelphia Eagles0-2.000L2

NFC North

#ClubW-LPCTStreak

1Detroit Lions1-1.500W1

2Minnesota Vikings1-1.500L1

3Green Bay Packers1-1.500W1

4Chicago Bears1-1.500L1

NFC South

#ClubW-LPCTStreak

1Tampa Bay Buccaneers2-01.000W2

2Carolina Panthers2-1.667W1

3Atlanta Falcons1-1.500W1

4New Orleans Saints0-2.000L2

NFC West

#ClubW-LPCTStreak

1Los Angeles Rams2-01.000W2

2San Francisco 49ers1-1.500W1

3Arizona Cardinals1-2.333L1

4Seattle Seahawks0-2.000L2

Win probability

San Francisco 49ers

49%

Kansas City Chiefs

51%

San Francisco 49ers vs Kansas City Chiefs — Dec 27, 2026

The read

What's at stake

Injury report

Projected starting lineups

League standings

Win probability

San Francisco 49ers vs Kansas City Chiefs — Dec 27, 2026

The read

What's at stake

Injury report

Projected starting lineups

League standings

Win probability