Arizona Cardinals vs Los Angeles Chargers

atCardinals at Chargers

Week 1

September 13 · 4:25 PM EDT

· LAC -10.5 · O/U 46.5

The read

There's a playoff line running through this one: Chargers sit in a postseason spot, while Cardinals are on the outside chasing a crossover, so it means a little more to the club playing from behind. Momentum cuts both ways: ARI arrive coming off a loss, LAC coming off a loss.

What's at stake

Where a win or a loss leaves each side.

Where they standLast 5Last 5Record

Arizona Cardinals3rd in the NFC West, 1.5 backLWLLLL10-0Away

Los Angeles Chargers1st in the AFC WestLWLLLL10-0Home

Injury report

Who is unavailable, in each club’s own words to the league. A day-to-day designation still allows a start, so a name here is not always a scratch; an injured-list stint is.

Arizona Cardinals5 listed

James ConnerRB · is questionable. Back 2026-08-28.

Jeremiyah LoveRB · is questionable. Back 2026-09-13.

Trey BensonRB · is listed injured reserve. Back 2027-02-15.

Xavier WeaverWR · is listed injured reserve. Back 2027-02-15.

Carson BeckQB · is questionable. Back 2026-08-28.

Los Angeles Chargers5 listed

Keaton MitchellRB · is questionable. Back 2026-08-27.

Brenen ThompsonWR · is questionable. Back 2026-08-27.

Tyler BiadaszCatcher · is listed injured reserve. Back 2027-02-15.

Tre' HarrisWR · is questionable. Back 2026-08-27.

Rashawn SlaterOT · is questionable. Back 2026-08-27.

Projected starting lineups

Each club's published depth chart, top of the order at every spot. A chart is not a game plan, and coaches confirm the actual card closer to kickoff.

Arizona CardinalsDepth chart

Offense11

Jacoby Brissett#76' 4"11 yr

Jeremiyah Love#46' 0"RookieQuestionable

Marvin Harrison Jr.#186' 3"3 yr

Michael Wilson#146' 2"4 yr

Kendrick Bourne#176' 1"10 yr

Trey McBride#856' 4"5 yr

Paris Johnson Jr.#706' 6"4 yr

Isaac Seumalo#736' 4"11 yr

Hjalte Froholdt#726' 5"8 yr

Isaiah Adams#746' 4"3 yr

Elijah Wilkinson#656' 6"10 yr

Defense11

LDE

Josh Sweat#106' 5"9 yr

LDT

Roy Lopez#516' 2"6 yr

RDT

Walter Nolen III#976' 4"2 yr

RDE

Darius Robinson#566' 5"3 yr

WLB

Cody Simon#06' 2"2 yr

MLB

Mack Wilson Sr.#16' 1"8 yr

SLB

Zaven Collins#256' 4"6 yr

LCB

Will Johnson#26' 2"2 yr

RCB

Denzel Burke#295' 11"2 yr

Budda Baker#35' 10"10 yr

Andrew Wingard#276' 0"8 yr

Special teams5

Chad Ryland#386' 0"4 yr

Blake Gillikin#126' 2"7 yrQuestionable

Casey Kreiter#596' 1"11 yr

Devin Duvernay#815' 11"6 yr

Los Angeles ChargersDepth chart

Offense11

Justin Herbert#106' 6"7 yr

Omarion Hampton#86' 0"2 yr

Ladd McConkey#156' 0"3 yr

Quentin Johnston#16' 2"4 yrQuestionable

Tre' Harris#96' 3"2 yrQuestionable

Charlie Kolar#886' 6"5 yr

Rashawn Slater#706' 4"6 yrQuestionable

Kayode Awosika#746' 3"5 yr

Jake Slaughter#666' 5"Rookie

Cole Strange#696' 5"5 yr

Joe Alt#766' 8"3 yr

Defense11

LDE

Teair Tart#936' 2"7 yr

Dalvin Tomlinson#946' 3"10 yr

RDE

Jamaree Caldwell#996' 1"2 yr

WLB

Tuli Tuipulotu#456' 3"4 yr

LILB

Daiyan Henley#06' 0"4 yr

RILB

Denzel Perryman#65' 11"12 yr

SLB

Khalil Mack#526' 3"13 yr

LCB

Cam Hart#206' 2"3 yr

RCB

Donte Jackson#265' 10"8 yr

Derwin James Jr.#36' 2"9 yr

Elijah Molden#25' 10"6 yr

Special teams5

Cameron Dicker#116' 1"5 yr

JK Scott#166' 5"8 yr

Josh Harris#476' 1"15 yr

Derius Davis#125' 8"4 yr

League standings

The full ladder, with both clubs marked.

AFC East

#ClubW-LPCTStreak

1Buffalo Bills2-01.000W2

2New England Patriots1-0.750W1

3New York Jets1-1.500W1

4Miami Dolphins0-2.000L2

AFC North

#ClubW-LPCTStreak

1Cincinnati Bengals2-01.000W2

2Baltimore Ravens2-01.000W2

3Pittsburgh Steelers1-1.500L1

4Cleveland Browns0-2.000L2

AFC South

#ClubW-LPCTStreak

1Tennessee Titans2-01.000W2

2Jacksonville Jaguars1-1.500L1

3Indianapolis Colts0-1.250L1

4Houston Texans0-2.000L2

AFC West

#ClubW-LPCTStreak

1Los Angeles Chargers1-1.500L1

2Las Vegas Raiders1-1.500W1

3Denver Broncos1-1.500L1

4Kansas City Chiefs0-2.000L2

NFC East

#ClubW-LPCTStreak

1Dallas Cowboys2-01.000W2

2Washington Commanders1-1.500L1

3New York Giants1-1.500W1

4Philadelphia Eagles0-2.000L2

NFC North

#ClubW-LPCTStreak

1Detroit Lions1-1.500W1

2Minnesota Vikings1-1.500L1

3Green Bay Packers1-1.500W1

4Chicago Bears1-1.500L1

NFC South

#ClubW-LPCTStreak

1Tampa Bay Buccaneers2-01.000W2

2Carolina Panthers2-1.667W1

3Atlanta Falcons1-1.500W1

4New Orleans Saints0-2.000L2

NFC West

#ClubW-LPCTStreak

1Los Angeles Rams2-01.000W2

2San Francisco 49ers1-1.500W1

3Arizona Cardinals1-2.333L1

4Seattle Seahawks0-2.000L2

Win probability

Arizona Cardinals

19%

Los Angeles Chargers

81%

Cardinals at Chargers

Arizona

Cardinals

Los Angeles

Chargers

Post Game SummaryStat Savant

atCardinals at Chargers

Week 1

September 13 · 4:25 PM EDT

· LAC -10.5 · O/U 46.5

The read

What's at stake

Where a win or a loss leaves each side.

Where they standLast 5Last 5Record

Arizona Cardinals3rd in the NFC West, 1.5 backLWLLLL10-0Away

Los Angeles Chargers1st in the AFC WestLWLLLL10-0Home

Injury report

Who is unavailable, in each club’s own words to the league. A day-to-day designation still allows a start, so a name here is not always a scratch; an injured-list stint is.

Arizona Cardinals5 listed

James ConnerRB · is questionable. Back 2026-08-28.

Jeremiyah LoveRB · is questionable. Back 2026-09-13.

Trey BensonRB · is listed injured reserve. Back 2027-02-15.

Xavier WeaverWR · is listed injured reserve. Back 2027-02-15.

Carson BeckQB · is questionable. Back 2026-08-28.

Los Angeles Chargers5 listed

Keaton MitchellRB · is questionable. Back 2026-08-27.

Brenen ThompsonWR · is questionable. Back 2026-08-27.

Tyler BiadaszCatcher · is listed injured reserve. Back 2027-02-15.

Tre' HarrisWR · is questionable. Back 2026-08-27.

Rashawn SlaterOT · is questionable. Back 2026-08-27.

Projected starting lineups

Each club's published depth chart, top of the order at every spot. A chart is not a game plan, and coaches confirm the actual card closer to kickoff.

Arizona CardinalsDepth chart

Offense11

Jacoby Brissett#76' 4"11 yr

Jeremiyah Love#46' 0"RookieQuestionable

Marvin Harrison Jr.#186' 3"3 yr

Michael Wilson#146' 2"4 yr

Kendrick Bourne#176' 1"10 yr

Trey McBride#856' 4"5 yr

Paris Johnson Jr.#706' 6"4 yr

Isaac Seumalo#736' 4"11 yr

Hjalte Froholdt#726' 5"8 yr

Isaiah Adams#746' 4"3 yr

Elijah Wilkinson#656' 6"10 yr

Defense11

LDE

Josh Sweat#106' 5"9 yr

LDT

Roy Lopez#516' 2"6 yr

RDT

Walter Nolen III#976' 4"2 yr

RDE

Darius Robinson#566' 5"3 yr

WLB

Cody Simon#06' 2"2 yr

MLB

Mack Wilson Sr.#16' 1"8 yr

SLB

Zaven Collins#256' 4"6 yr

LCB

Will Johnson#26' 2"2 yr

RCB

Denzel Burke#295' 11"2 yr

Budda Baker#35' 10"10 yr

Andrew Wingard#276' 0"8 yr

Special teams5

Chad Ryland#386' 0"4 yr

Blake Gillikin#126' 2"7 yrQuestionable

Casey Kreiter#596' 1"11 yr

Devin Duvernay#815' 11"6 yr

Los Angeles ChargersDepth chart

Offense11

Justin Herbert#106' 6"7 yr

Omarion Hampton#86' 0"2 yr

Ladd McConkey#156' 0"3 yr

Quentin Johnston#16' 2"4 yrQuestionable

Tre' Harris#96' 3"2 yrQuestionable

Charlie Kolar#886' 6"5 yr

Rashawn Slater#706' 4"6 yrQuestionable

Kayode Awosika#746' 3"5 yr

Jake Slaughter#666' 5"Rookie

Cole Strange#696' 5"5 yr

Joe Alt#766' 8"3 yr

Defense11

LDE

Teair Tart#936' 2"7 yr

Dalvin Tomlinson#946' 3"10 yr

RDE

Jamaree Caldwell#996' 1"2 yr

WLB

Tuli Tuipulotu#456' 3"4 yr

LILB

Daiyan Henley#06' 0"4 yr

RILB

Denzel Perryman#65' 11"12 yr

SLB

Khalil Mack#526' 3"13 yr

LCB

Cam Hart#206' 2"3 yr

RCB

Donte Jackson#265' 10"8 yr

Derwin James Jr.#36' 2"9 yr

Elijah Molden#25' 10"6 yr

Special teams5

Cameron Dicker#116' 1"5 yr

JK Scott#166' 5"8 yr

Josh Harris#476' 1"15 yr

Derius Davis#125' 8"4 yr

League standings

The full ladder, with both clubs marked.

AFC East

#ClubW-LPCTStreak

1Buffalo Bills2-01.000W2

2New England Patriots1-0.750W1

3New York Jets1-1.500W1

4Miami Dolphins0-2.000L2

AFC North

#ClubW-LPCTStreak

1Cincinnati Bengals2-01.000W2

2Baltimore Ravens2-01.000W2

3Pittsburgh Steelers1-1.500L1

4Cleveland Browns0-2.000L2

AFC South

#ClubW-LPCTStreak

1Tennessee Titans2-01.000W2

2Jacksonville Jaguars1-1.500L1

3Indianapolis Colts0-1.250L1

4Houston Texans0-2.000L2

AFC West

#ClubW-LPCTStreak

1Los Angeles Chargers1-1.500L1

2Las Vegas Raiders1-1.500W1

3Denver Broncos1-1.500L1

4Kansas City Chiefs0-2.000L2

NFC East

#ClubW-LPCTStreak

1Dallas Cowboys2-01.000W2

2Washington Commanders1-1.500L1

3New York Giants1-1.500W1

4Philadelphia Eagles0-2.000L2

NFC North

#ClubW-LPCTStreak

1Detroit Lions1-1.500W1

2Minnesota Vikings1-1.500L1

3Green Bay Packers1-1.500W1

4Chicago Bears1-1.500L1

NFC South

#ClubW-LPCTStreak

1Tampa Bay Buccaneers2-01.000W2

2Carolina Panthers2-1.667W1

3Atlanta Falcons1-1.500W1

4New Orleans Saints0-2.000L2

NFC West

#ClubW-LPCTStreak

1Los Angeles Rams2-01.000W2

2San Francisco 49ers1-1.500W1

3Arizona Cardinals1-2.333L1

4Seattle Seahawks0-2.000L2

Win probability

Arizona Cardinals

19%

Los Angeles Chargers

81%

Arizona Cardinals vs Los Angeles Chargers — Sep 13, 2026

The read

What's at stake

Injury report

Projected starting lineups

League standings

Win probability

Arizona Cardinals vs Los Angeles Chargers — Sep 13, 2026

The read

What's at stake

Injury report

Projected starting lineups

League standings

Win probability