Rivalry · NFL · Bills vs. Panthers · Every meeting since 2017
Bills vs. Panthers
Bills vs. Panthers: Buffalo leads 2-1 since 2017
Buffalo has won two of the three meetings since 2017. The last meeting went to the Bills, 40-9 in Carolina, in October 2025.
Buffalo has won two of the three meetings since 2017. The last meeting went to the Bills, 40-9 in Carolina, in October 2025.
2Bills wins · 74 points
1Panthers wins · 32 points
In BuffaloBills 1-0
In CarolinaBills 1-1
Last fourBills 2-1
Every meeting
Newest firstOct 26, 2025Bills 40, Panthers 9Week 8 · in Carolina
Bills 40, Panthers 9Week 8 · in CarolinaDec 19, 2021Bills 31, Panthers 14Week 15 · in Buffalo
Bills 31, Panthers 14Week 15 · in BuffaloSep 17, 2017Panthers 9, Bills 3Week 2 · in Carolina
Panthers 9, Bills 3Week 2 · in CarolinaEvery game the two have played since the 2017 season, regular season and playoffs, from the results we store. Dates are Eastern.