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Minnesota Twins vs San Francisco Giants — Sep 22, 2026

Minnesota
Twins
70-80
September 22 · 9:45 PM EDT
San Francisco
Giants
62-89

What to look for

The written preview lands about a day and a half before the game, once the lineups, the injuries and the market have settled. Until then the boards below carry the matchup: recent form, how the two sides compare, and where each of them sits.

The full preview, matchup keys, probable starters and the storylines to watch, posts closer to game time, once lineups are set.

Last five games

Each side's most recent results, newest first, with the score and who they played. These reach back into last season where a club has not played five yet, which is why every row carries its date.

Minnesota Twins
  • 09/14/26L3-8vsYankees
  • 09/13/26L2-9vsGuardians
  • 09/12/26W4-3vsGuardians
  • 09/12/26L2-5vsGuardians
  • 09/09/26L2-7atTigers
San Francisco Giants
  • 09/14/26L1-2atCardinals
  • 09/13/26L4-6vsPadres
  • 09/12/26L6-7vsPadres
  • 09/12/26L5-7vsPadres
  • 09/09/26W7-6vsCardinals

Standings

Where each side sits in its own division, with both clubs marked. These two are in different ones, so the tables are separate and the records are not directly comparable.

AL Central
#ClubW-LPCTStreak
1Chicago White Sox77-73.513W1
2Cleveland Guardians76-75.503L1
3Detroit Tigers71-79.473W5
4Minnesota Twins70-80.467L2
5Kansas City Royals66-84.440L2
NL West
#ClubW-LPCTStreak
1Los Angeles Dodgers91-59.607W1
2San Diego Padres81-68.544W7
3Arizona Diamondbacks79-71.527L2
4San Francisco Giants62-89.411L4
5Colorado Rockies55-94.369L7

Every game on the slate today

  • Durham Bulls at Worcester Red SoxAAA · 6:05 PM
  • Indianapolis Indians at Lawrenceville StripersAAA · 6:05 PM
  • Rochester Red Wings at Buffalo BisonsAAA · 6:05 PM
  • Winston-Salem Dash at Greensboro GrasshoppersA+ · 6:30 PM
  • Tampa Tarpons at Jupiter HammerheadsA · 6:30 PM
  • Richmond Flying Squirrels at Erie SeaWolvesAA · 6:35 PM
  • Allentown IronPigs at Syracuse MetsAAA · 6:35 PM
  • St. Paul Saints at Columbus ClippersAAA · 6:35 PM
  • Charlotte Knights at Norfolk TidesAAA · 6:35 PM
  • Louisville Bats at Toledo Mud HensAAA · 6:35 PM
  • Charleston RiverDogs at Fayetteville WoodpeckersA · 6:35 PM
  • Los Angeles Dodgers at Cincinnati RedsMLB · 6:40 PM
  • Chicago White Sox at Cleveland GuardiansMLB · 6:40 PM
  • Oakland Athletics at Tampa Bay RaysMLB · 6:40 PM
  • Milwaukee Brewers at Pittsburgh PiratesMLB · 6:40 PM
  • Hartford Yard Goats at Reading Fightin PhilsAA · 6:45 PM
  • Philadelphia Phillies at Washington NationalsMLB · 6:45 PM
  • Biloxi Shuckers at Pensacola Blue WahoosAA · 7:05 PM
  • Jacksonville Jumbo Shrimp at Moosic RailRidersAAA · 7:05 PM
  • Davenport River Bandits at Dayton DragonsA+ · 7:05 PM
  • Detroit Tigers at Toronto Blue JaysMLB · 7:07 PM
  • Baltimore Orioles at New York MetsMLB · 7:10 PM
  • Tulsa Drillers at Springfield CardinalsAA · 7:35 PM
  • Frisco RoughRiders at Amarillo Sod PoodlesAA · 7:35 PM
  • Knoxville Smokies at Madison Trash PandasAA · 7:35 PM
  • Des Moines Cubs at Papillion Storm ChasersAAA · 7:35 PM
  • Memphis Redbirds at Nashville SoundsAAA · 7:35 PM
  • Atlanta Braves at Chicago CubsMLB · 7:40 PM
  • New York Yankees at Minnesota TwinsMLB · 7:40 PM
  • Tacoma Rainiers at Round Rock ExpressAAA · 7:45 PM
  • San Francisco Giants at St. Louis CardinalsMLB · 7:45 PM
  • Las Vegas Aviators at Sugar Land Space CowboysAAA · 8:05 PM
  • Boston Red Sox at Texas RangersMLB · 8:05 PM
  • Kansas City Royals at Houston AstrosMLB · 8:10 PM
  • South Jordan Bees at Albuquerque IsotopesAAA · 8:35 PM
  • Oklahoma City Comets at El Paso ChihuahuasAAA · 8:35 PM
  • San Diego Padres at Colorado RockiesMLB · 8:40 PM
  • Lake Elsinore Storm at San Jose GiantsA · 9:30 PM
  • Seattle Mariners at Los Angeles AngelsMLB · 9:38 PM
  • Miami Marlins at Arizona DiamondbacksMLB · 9:40 PM
  • Reno Aces at Sacramento River CatsAAA · 9:45 PM
Highlight
How it WorksMajor LeaguePremium ContentSports BettingNews Wire

Highlights is an email-first sports service: you follow the teams you care about, and we send the previews, recaps, box scores and news that belong to them. No app to install, no feed to scroll, and every email is free to start and takes one click to stop.

Scores, schedules, rosters, and statistics are aggregated from public sports data feeds and are provided for informational purposes only. Odds, projections, and win probabilities are for entertainment only and are not betting advice. Team names and marks belong to their respective owners and are used to identify the clubs we cover.

© 2026 MainMarket.com. All rights reserved.

Terms of UsePrivacy Policy