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Cleveland Guardians vs Boston Red Sox — Sep 22, 2026

Cleveland
Guardians
76-74
September 22 · 6:45 PM EDT
Boston
Red Sox
82-68

What to look for

The written preview lands about a day and a half before the game, once the lineups, the injuries and the market have settled. Until then the boards below carry the matchup: recent form, how the two sides compare, and where each of them sits.

The full preview, matchup keys, probable starters and the storylines to watch, posts closer to game time, once lineups are set.

Last five games

Each side's most recent results, newest first, with the score and who they played. These reach back into last season where a club has not played five yet, which is why every row carries its date.

Cleveland Guardians
  • 09/13/26W9-2atTwins
  • 09/12/26L3-4atTwins
  • 09/12/26W5-2atTwins
  • 09/09/26L5-9atOrioles
  • 09/08/26W9-5atOrioles
Boston Red Sox
  • 09/13/26W4-1vsRoyals
  • 09/12/26W5-1vsRoyals
  • 09/11/26L2-3vsRoyals
  • 09/09/26L4-6vsAngels
  • 09/08/26L1-6vsAngels

Standings

Where each side sits in its own division, with both clubs marked. These two are in different ones, so the tables are separate and the records are not directly comparable.

AL Central
#ClubW-LPCTStreak
1Chicago White Sox76-73.510L1
2Cleveland Guardians76-74.507W1
3Minnesota Twins70-79.470L1
4Detroit Tigers70-79.470W4
5Kansas City Royals66-84.440L2
AL East
#ClubW-LPCTStreak
1Tampa Bay Rays90-59.604W3
2New York Yankees86-63.577W1
3Boston Red Sox82-68.547W2
4Toronto Blue Jays75-75.500W2
5Baltimore Orioles72-78.480L2

Every game on the slate today

  • Newcastle United at Leeds UnitedEPL · Final
  • Chicago White Sox at Cleveland GuardiansMLB · Mid 5th
  • Los Angeles Dodgers at Cincinnati RedsMLB · Top 6th
  • Detroit Tigers at Toronto Blue JaysMLB · Bot 3rd
  • Baltimore Orioles at New York MetsMLB · Mid 3rd
  • Atlanta Braves at Chicago CubsMLB · Mid 2nd
  • New York Yankees at Minnesota TwinsMLB · Top 2nd
  • San Francisco Giants at St. Louis CardinalsMLB · Bot 1st
  • Denver Broncos at Kansas City ChiefsNFL · 2:55 - 1st
  • San Diego Padres at Colorado RockiesMLB · 8:40 PM
  • Seattle Mariners at Los Angeles AngelsMLB · 9:38 PM
  • Miami Marlins at Arizona DiamondbacksMLB · 9:40 PM
Highlight
How it WorksMajor LeaguePremium ContentSports BettingNews Wire

Highlights is an email-first sports service: you follow the teams you care about, and we send the previews, recaps, box scores and news that belong to them. No app to install, no feed to scroll, and every email is free to start and takes one click to stop.

Scores, schedules, rosters, and statistics are aggregated from public sports data feeds and are provided for informational purposes only. Odds, projections, and win probabilities are for entertainment only and are not betting advice. Team names and marks belong to their respective owners and are used to identify the clubs we cover.

© 2026 MainMarket.com. All rights reserved.

Terms of UsePrivacy Policy